Andrzej T Slominski Selected Research

Secosteroids

1/2021	Editorial: Steroids and Secosteroids in the Modulation of Inflammation and Immunity.
10/2014	The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.
1/2014	Cytochromes p450 and skin cancer: role of local endocrine pathways.
5/2013	Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.
9/2012	Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength.
9/2012	Novel vitamin D hydroxyderivatives inhibit melanoma growth and show differential effects on normal melanocytes.
5/2012	New vitamin D analogs as potential therapeutics in melanoma.
1/2011	Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity.
3/2010	Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Andrzej T Slominski Research Topics

Disease

60	Melanoma (Melanoma, Malignant) 01/2022 - 08/2003
34	Neoplasms (Cancer) 01/2022 - 12/2008
11	Neoplasm Metastasis (Metastasis) 11/2021 - 05/2011
8	Skin Neoplasms (Skin Cancer) 01/2022 - 01/2014
6	COVID-19 02/2022 - 01/2020
6	Skin Diseases (Skin Disease) 01/2022 - 06/2009
6	Inflammation (Inflammations) 12/2021 - 12/2003
5	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 03/2011
4	Carcinogenesis 12/2021 - 01/2014
3	Carcinoma (Carcinomatosis) 01/2022 - 02/2015
3	Fibrosis (Cirrhosis) 12/2021 - 01/2021
3	Rheumatoid Arthritis 12/2021 - 01/2020
3	Autoimmune Diseases (Autoimmune Disease) 12/2021 - 01/2020
3	Urinary Bladder Neoplasms (Bladder Cancer) 03/2016 - 10/2015
3	Nevus (Nevi) 10/2014 - 05/2011
2	Infections 02/2022 - 01/2021
2	Hypoxia (Hypoxemia) 01/2022 - 01/2019
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022 - 01/2021
2	Arthritis (Polyarthritis) 12/2021 - 01/2021
2	Wounds and Injuries (Trauma) 10/2021 - 05/2021
2	Ovarian Neoplasms (Ovarian Cancer) 11/2020 - 02/2015
2	Hypercalcemia (Milk Alkali Syndrome) 05/2020 - 10/2014
2	Atopic Dermatitis (Atopic Eczema) 01/2020 - 12/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 11/2018 - 11/2017
2	Pigmented Nevus (Melanocytic Nevus) 01/2018 - 10/2014
2	Pathologic Processes 09/2016 - 04/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2016 - 08/2015
2	Smith-Lemli-Opitz Syndrome 07/2015 - 02/2009
1	Virus Diseases (Viral Diseases) 02/2022
1	Neurodermatitis (Lichen Simplex Chronicus) 01/2022
1	Allergic Contact Dermatitis 01/2022
1	Sarcoidosis (Schaumann Disease) 01/2022
1	Systemic Scleroderma (Systemic Sclerosis) 12/2021
1	Experimental Arthritis 12/2021
1	Muscle Cramp (Cramp) 10/2021

Drug/Important Bio-Agent (IBA)

31	Vitamin D FDA LinkGeneric 01/2022 - 05/2011
24	hydroxide ionIBA 12/2021 - 03/2010
18	Calcitriol (Calcijex)FDA LinkGeneric 01/2022 - 02/2009
15	Melanins (Melanin)IBA 01/2022 - 09/2008
14	20-hydroxyvitamin D3IBA 12/2021 - 03/2010
12	MelatoninIBA 02/2022 - 04/2012
12	Cholecalciferol (Vitamin D3)FDA Link 01/2022 - 12/2008
12	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2022 - 05/2011
9	SecosteroidsIBA 01/2021 - 03/2010
9	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 01/2019 - 03/2013
8	Vitamin D3 24-HydroxylaseIBA 01/2022 - 10/2014
8	Cholesterol Side-Chain Cleavage Enzyme (CYP11A1)IBA 05/2020 - 03/2010
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2015
6	Biological ProductsIBA 04/2021 - 12/2008
5	VitaminsIBA 01/2022 - 05/2012
5	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022 - 09/2016
5	Messenger RNA (mRNA)IBA 12/2021 - 03/2015
5	AgarIBA 12/2017 - 09/2012
4	EnzymesIBA 01/2021 - 03/2013
3	Pharmaceutical PreparationsIBA 02/2022 - 03/2007
3	CollagenIBA 12/2021 - 01/2021
3	CytokinesIBA 12/2021 - 01/2021
3	1alpha,20-dihydroxyvitamin D3IBA 06/2021 - 01/2020
3	CalciumIBA 06/2021 - 01/2017
3	Tyrosine (L-Tyrosine)FDA Link 05/2021 - 01/2010
3	Monophenol Monooxygenase (Tyrosinase)IBA 05/2021 - 08/2003
3	SteroidsIBA 01/2021 - 01/2014
2	Antiviral Agents (Antivirals)IBA 02/2022 - 01/2021
2	AntioxidantsIBA 02/2022 - 01/2020
2	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2022 - 01/2022
2	AntibodiesIBA 12/2021 - 01/2021
2	Serotonin (5 Hydroxytryptamine)IBA 04/2021 - 03/2020
2	Ergosterol (Lumisterol)IBA 01/2021 - 03/2015
2	GlucocorticoidsIBA 01/2020 - 01/2017
2	Protective AgentsIBA 01/2020 - 09/2014
2	Hormones (Hormone)IBA 05/2019 - 05/2009
2	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 01/2016
2	RetinoidsIBA 01/2019 - 08/2015
2	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2019 - 05/2011
2	Melatonin Receptors (Melatonin Receptor)IBA 11/2018 - 04/2012
2	calcipotriene (calcipotriol)FDA LinkGeneric 08/2018 - 03/2015
2	Cytochrome P-450 CYP3AIBA 08/2018 - 05/2016
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2017 - 02/2016
2	Indicators and Reagents (Reagents)IBA 03/2016 - 02/2015
2	diazonaphthalenedisulfonic acid (NDS)IBA 02/2016 - 10/2015
2	CholesterolIBA 01/2016 - 08/2015
2	N-acetyl-N-formyl-5-methoxykynurenamineIBA 03/2015 - 07/2013
2	7-dehydrocholesterolIBA 03/2010 - 02/2009
2	Corticotropin-Releasing HormoneIBA 06/2004 - 12/2003
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 02/2022
1	Neuropeptide YIBA 01/2022
1	AntigensIBA 01/2022
1	Hydroxyl RadicalIBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 12/2021
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	DefensinsIBA 10/2021
1	CathelicidinsIBA 10/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 08/2021
1	3- hydroxyandrosta- 5,7- diene- 17- carboxylic acidIBA 08/2021

Therapy/Procedure

26	Therapeutics 01/2022 - 09/2008
3	Drug Therapy (Chemotherapy) 01/2022 - 10/2013
3	Radiotherapy 04/2016 - 09/2008
2	Immunotherapy 01/2022 - 02/2016
1	Injections 08/2021